Dementia Today.net

Site updated at Wednesday, 22 June 2016

Living with Dementia

Alpha Synuclein

Types of Dementia Parkinson’s Disease

Parkinson’s Disease is a common disorder of deep brain structures that help control movement. Over time, many people with Parkinson’s disease develop Parkinson’s Disease Dementia. The majority of Parkinson’s Disease patients over the age if 65 develop dementia within a few years. Even younger people with Parkinson’s Disease can develop dementia -  one community… Types of Dementia Parkinson’s Disease   



New clue to Parkinson’s

A new study finds that a protein key to Parkinson’s disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging existing disease paradigms and suggesting a new therapeutic approach.

“Our data show that alpha-synuclein was essentially mistakenly characterized as a natively unfolded… New clue to Parkinson’s   



New research reveals how alpha-synuclein interacts with cell membranes in Parkinson’s disease

The accumulation of α-synuclein, a small, negatively charged protein, in neural cells, is one of the hallmarks of Parkinson’s disease. It has been suggested that oligomeric α-synuclein causes membranes to become permeable, or to form channels on the outer cell membrane. Now, a group of scientists from Sweden has found a way to reliably… New research reveals how alpha-synuclein interacts with cell membranes in Parkinson’s disease   



Early signs of Parkinson’s might be seen in colon

A colonoscopy or similar test could one day diagnose Parkinson’s disease years before symptoms occur. That’s because signs of Parkinson’s that appear in the brain also show up in the colon, a new study says.

Researchers examined tissue samples obtained during colon exams of people who later developed Parkinson’s disease. The samples were taken… Early signs of Parkinson’s might be seen in colon   



Mechanism that leads to sporadic Parkinson’s disease identified

Researchers in the Taub Institute at Columbia University Medical Center (CUMC) have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson’s disease, the progressive movement disorder. The discovery highlights potential new therapeutic targets for Parkinson’s and could lead to a blood test for the disease. The study, based… Mechanism that leads to sporadic Parkinson’s disease identified   



Biomarkers in cerebrospinal fluid can identify patients with Alzheimer’s disease

Analysis of specific biomarkers in a cerebrospinal fluid sample can differentiate patients with Alzheimer’s disease from those with other types of dementia. The method, which is being studied by researchers at Sahlgrenska Academy, may eventually permit earlier detection of Alzheimer’s disease.

Due to the similarity of the symptoms, differentiating patients with Alzheimer’s from those… Biomarkers in cerebrospinal fluid can identify patients with Alzheimer’s disease   



Genetic mutation increases risk of Parkinson’s disease from pesticides

A team of researchers has brought new clarity to the picture of how gene-environmental interactions can kill nerve cells that make dopamine. Dopamine is the neurotransmitter that sends messages to the part of the brain that controls movement and coordination. Their discoveries, described in a paper published online in Cell today, include identification… Genetic mutation increases risk of Parkinson’s disease from pesticides   



Living with Dementia

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