Dementia Today.net

Site updated at Wednesday, 22 June 2016

Living with Dementia

Amyloid Beta Protein

Study confirms that rare mutations increase risk of late-onset Alzheimer’s disease

Massachusetts General Hospital (MGH) researchers have identified and validated two rare gene mutations that appear to cause the common form of Alzheimer’s disease (AD) that strikes after the age of 60. The two mutations occur in a gene called ADAM10 - coding for an enzyme involved in processing the amyloid precursor protein - which… Study confirms that rare mutations increase risk of late-onset Alzheimer’s disease   



Alzheimer’s researchers find clues to toxic forms of amyloid beta

Much of the research on Alzheimer’s disease has focused on the amyloid beta protein, which clumps together into sticky fibrils that form deposits in the brains of people with the disease. In recent years, attention has turned away from the fibrils themselves to an intermediate stage in the aggregation of amyloid beta. “Oligomers” consisting… Alzheimer’s researchers find clues to toxic forms of amyloid beta   



Alzheimer’s Disease

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