Researchers at the University of Toronto Scarborough (UTSC) and Osaka University applied a new approach to take a close look at amyloid plaque formation, a process that plays important roles in Alzheimer’s disease. The technique would greatly aid the development and screening for novel therapeutics that can manipulate the formation of the toxic amyloid…    



Keeping brain sharp may ward off Alzheimer’s protein

People who challenge their brains throughout their lifetimes - through reading, writing and playing games - are less likely to develop protein deposits in the brain linked with Alzheimer’s, researchers said on Monday.

Prior studies have suggested that people who are well educated and stay mentally active build up brain reserves that allow them…    



Protein in the brain could be a key target in controlling Alzheimer’s

A protein recently discovered in the brain could play a key role in regulating the creation of amyloid beta, the major component of plaques implicated in the development of Alzheimer’s disease, according to researchers at Temple University’s School of Medicine.

A group led by Domenico Pratico, professor of pharmacology and microbiology and immunology at…    



It’s not just amyloid: White matter hyperintensities and Alzheimer’s disease

New findings by Columbia researchers suggest that along with amyloid deposits, white matter hyperintensities (WMHs) may be a second necessary factor for the development of Alzheimer’s disease.

Most current approaches to Alzheimer’s disease focus on the accumulation of amyloid plaque in the brain. The researchers at the Taub Institute for Research on Alzheimer’s Disease…