Dementia Today.net

Site updated at Wednesday, 22 June 2016

Living with Dementia

Amyloid Precursor Protein

Alzheimer’s Disease Study Shows How The Disease Progresses

Scientists at the Wellcome Trust and Cancer Research UK Gurdon Institute in Cambridge New have made new progresses in the understanding of Alzheimer’s disease (AD). The study, published this in Science Translational Medicine, highlights the connection between Alzheimer’s disease and Down’ s syndrome.

The scientists used human induced pluripotent cell donated by volunteers with… Alzheimer’s Disease Study Shows How The Disease Progresses   



Laboratory Research Shows Promising Approach to Preventing Alzheimer’s

As scientists struggle to find an effective way to prevent Alzheimer’s disease, researchers at the University of Wisconsin-Madison may have found a new approach to interrupting the process that leads to the devastating disease.

Building on their knowledge of two enzymes that control an “uber” enzyme critical to the development of the disease, the… Laboratory Research Shows Promising Approach to Preventing Alzheimer’s   



Alzheimer’s precursor protein controls its own fate, study finds

A research team led by the University of South Florida Department of Psychiatry & Behavioral Neurosciences has found that a fragment of the amyloid precursor protein (APP) - known as sAPP-α and associated with Alzheimer’s disease - appears to regulate its own production. The finding may lead to ways to prevent or treat Alzheimer’s… Alzheimer’s precursor protein controls its own fate, study finds   



Study confirms that rare mutations increase risk of late-onset Alzheimer’s disease

Massachusetts General Hospital (MGH) researchers have identified and validated two rare gene mutations that appear to cause the common form of Alzheimer’s disease (AD) that strikes after the age of 60. The two mutations occur in a gene called ADAM10 - coding for an enzyme involved in processing the amyloid precursor protein - which… Study confirms that rare mutations increase risk of late-onset Alzheimer’s disease   



New mouse model could revolutionize research in Alzheimer’s disease

Alzheimer’s disease, the primary cause of dementia in the elderly, imposes a tremendous social and economic burden on modern society. In Japan, the burden of the disease in 2050 is estimated to be a half a trillion US dollars, a figure equivalent to the government’s annual revenues.

Unfortunately, it has proven very difficult to… New mouse model could revolutionize research in Alzheimer’s disease   



Alzheimer’s disease works differently in patients with and without Down syndrome

Researchers at the University of Kentucky’s Sanders-Brown Center on Aging have completed a study that revealed differences in the way brain inflammation - considered a key component of AD—is expressed in different subsets of patients, in particular people with Down syndrome (DS) and AD.

People with Down syndrome have a third copy of Chromosome… Alzheimer’s disease works differently in patients with and without Down syndrome   



Parkinson’s Disease Dementia

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