Dementia Today.net

Site updated at Wednesday, 22 June 2016

Living with Dementia

Amyloid Beta

Alzheimer’s missing link found

Yale School of Medicine researchers have discovered a protein that is the missing link in the complicated chain of events that lead to Alzheimer’s disease, they report in the Sept. 4 issue of the journal Neuron. Researchers also found that blocking the protein with an existing drug can restore memory in mice with brain… Alzheimer’s missing link found   



Uncovering first molecular missteps that drive neurons in pathway leading to Alzheimer’s disease

Much of the debate in Alzheimer’s disease (AD) has focused on whether the protein amyloid-beta or the tau protein is the symptom or the cause of the disease.

But George Bloom, Ph.D., and colleagues at the University of Virginia (UVA) have pursued another hypothesis: much earlier interactions between the two proteins them drive adult… Uncovering first molecular missteps that drive neurons in pathway leading to Alzheimer’s disease   



Uncovering first molecular missteps that drive neurons in pathway leading to Alzheimer’s disease

Much of the debate in Alzheimer’s disease (AD) has focused on whether the protein amyloid-beta or the tau protein is the symptom or the cause of the disease.

But George Bloom, Ph.D., and colleagues at the University of Virginia (UVA) have pursued another hypothesis: much earlier interactions between the two proteins them drive adult… Uncovering first molecular missteps that drive neurons in pathway leading to Alzheimer’s disease   



Molecular modeling of novel potent agents for treating Alzheimer’s disease

Alzheimer’s disease (AD), a severe form of dementia among aged individuals, is caused by accumulation of amyloid-beta (Aβ) peptides in the brain. Numerous types of agents have been developed to suppress the production of Aβ, by inhibiting the secretase-mediated cleavage of amyloid precursor protein (APP) into Aβ peptides.

However, because the secretases also play… Molecular modeling of novel potent agents for treating Alzheimer’s disease   



I have Alzheimer Disease

synaptic loss1 - deep brain stimulation2 - substantia nigra7 - alzheimers association1 - atypical alzheimer disease1 - delay dementia1 - memory restoration1 - memory impairment2 - arterial plaques1 - sleep loss1 - amyloid proteins1 - fuller1 - overweight1 - stupidity2 - medicare1 - risk of developing parkinson's1 - tasigna1 - coronary heart disease1 - wernicke syndrome1 - ziprasidone1 - degenerative dementia2 - university of pennsylvania2 - behavioral symptoms1 - dantrolene1 - brain health1 - margaret thatcher1 - mri2 - dementia risk4 - reversible dementia syndrome1 - meryl streep1 -