Dementia Today.net

Site updated at Wednesday, 22 June 2016

Living with Dementia

Amyloid Beta

Alzheimer’s missing link found

Yale School of Medicine researchers have discovered a protein that is the missing link in the complicated chain of events that lead to Alzheimer’s disease, they report in the Sept. 4 issue of the journal Neuron. Researchers also found that blocking the protein with an existing drug can restore memory in mice with brain… Alzheimer’s missing link found   



Uncovering first molecular missteps that drive neurons in pathway leading to Alzheimer’s disease

Much of the debate in Alzheimer’s disease (AD) has focused on whether the protein amyloid-beta or the tau protein is the symptom or the cause of the disease.

But George Bloom, Ph.D., and colleagues at the University of Virginia (UVA) have pursued another hypothesis: much earlier interactions between the two proteins them drive adult… Uncovering first molecular missteps that drive neurons in pathway leading to Alzheimer’s disease   



Uncovering first molecular missteps that drive neurons in pathway leading to Alzheimer’s disease

Much of the debate in Alzheimer’s disease (AD) has focused on whether the protein amyloid-beta or the tau protein is the symptom or the cause of the disease.

But George Bloom, Ph.D., and colleagues at the University of Virginia (UVA) have pursued another hypothesis: much earlier interactions between the two proteins them drive adult… Uncovering first molecular missteps that drive neurons in pathway leading to Alzheimer’s disease   



Molecular modeling of novel potent agents for treating Alzheimer’s disease

Alzheimer’s disease (AD), a severe form of dementia among aged individuals, is caused by accumulation of amyloid-beta (Aβ) peptides in the brain. Numerous types of agents have been developed to suppress the production of Aβ, by inhibiting the secretase-mediated cleavage of amyloid precursor protein (APP) into Aβ peptides.

However, because the secretases also play… Molecular modeling of novel potent agents for treating Alzheimer’s disease   



What is dementia?

parkinson's disease59 - mild alzheimer's disease1 - dementia progression1 - prion disease1 - rem-sleep behavior disorder1 - amyloid markers1 - interviews by magistrates1 - miller fisher1 - solanezumab1 - apolipoprotein e2 - exercise games1 - mildcognitive impairment1 - misplacing things1 - hallucinoses1 - dementia of lewy body1 - parkinson's psychosis1 - problems with memory1 - meryl streep1 - long-term memory1 - brain injury1 - white matter hyperintensities1 - memory tests1 - neel nabar1 - alzheimer treatment1 - mid-stage of alzheimer's1 - circumscribed cerebral atrophy1 - american delirium society1 - developing alzheimers2 - impassable plaques1 - alzheimer's disease risk3 -