Site updated at Wednesday, 22 June 2016

Living with Dementia

Amyloid Targeting Treatment

Beta secretase inhibitors to treat Alzheimer’s disease

With each new amyloid-targeting treatment for Alzheimer’s disease that has been developed, there has been a corresponding concern. For example, antibodies targeting amyloid-β peptide (Aβ) produce inflammation in the brain in some patients. Gamma secretase inhibitors tend to produce adverse effects by interacting with Notch, an important pathway for cellular signaling.

Beta secretase 1… Beta secretase inhibitors to treat Alzheimer’s disease   


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