Site updated at Wednesday, 22 June 2016

Living with Dementia

Apolipoprotein E

Women Have Higher Genetic Risk of Alzheimer’s

A major genetic risk factor for Alzheimer’s disease - the E4 variant of the apolipoprotein E (APOE) gene - manifests itself more often in women than in men, researchers reported.

In a cohort of cognitively healthy older men and women, carrying the E4 variant was associated with deficits in brain connectivity in women, but… Women Have Higher Genetic Risk of Alzheimer’s   

Research suggests anti-inflammatory protein may trigger plaque in Alzheimer’s disease

Inflammation has long been studied in Alzheimer’s, but in a counterintuitive finding reported in a new paper, University of Florida researchers have uncovered the mechanism by which anti-inflammatory processes may trigger the disease.

This anti-inflammatory process might actually trigger the build-up of sticky clumps of protein that form plaques in the brain. These plaques… Research suggests anti-inflammatory protein may trigger plaque in Alzheimer’s disease   

Enid and George - Life with dementia

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