Dementia Today.net

Site updated at Wednesday, 22 June 2016

Living with Dementia

Cerebrospinal Fluid

New clues to the cause of Alzheimer’s disease

Researchers at the Sahlgrenska Academy, University of Gothenburg, have identified a series of novel proteins in human cerebrospinal fluid. The proteins, which carry specific sugar molecules, are found in greater concentrations in patients with dementia caused by Alzheimer’s disease than in patients with dementia caused by other diseases. This gives hope for new forms… New clues to the cause of Alzheimer’s disease   



People with Early Alzheimer’s Disease May Be More Likely to Have Lower BMI

Studies have shown that people who are overweight in middle age are more likely to develop Alzheimer’s disease decades later than people at normal weight, yet researchers have also found that people in the earliest stages of Alzheimer’s disease are more likely to have a lower body mass index (BMI). A current study examines… People with Early Alzheimer’s Disease May Be More Likely to Have Lower BMI   



Changes in Cerebrospinal Fluid May Signal Early Alzheimer’s

Searching for a better screen for early Alzheimer’s disease, researchers think they have found a marker of change in the brain that precedes the onset of the disease by five to 10 years.

The indicator of trouble to come, they say, is a shift in the levels of specific components of the cerebrospinal fluid… Changes in Cerebrospinal Fluid May Signal Early Alzheimer’s   



Alzheimer’s Markers Seen Way Before Symptoms

Beta amyloid protein measurements may begin to show abnormalities more than 2 decades before overt symptoms of Alzheimer’s disease appear, researchers said.

Imaging and cerebrospinal fluid (CSF) analyses of patients with a powerful genetic predisposition to Alzheimer’s disease showed that AB42 (a form of beta amyloid protein with 42 amino acids) levels began to… Alzheimer’s Markers Seen Way Before Symptoms   



Biomarkers in cerebrospinal fluid can identify patients with Alzheimer’s disease

Analysis of specific biomarkers in a cerebrospinal fluid sample can differentiate patients with Alzheimer’s disease from those with other types of dementia. The method, which is being studied by researchers at Sahlgrenska Academy, may eventually permit earlier detection of Alzheimer’s disease.

Due to the similarity of the symptoms, differentiating patients with Alzheimer’s from those… Biomarkers in cerebrospinal fluid can identify patients with Alzheimer’s disease   



MRI May Tell Alzheimer’s from Other Dementias

Three-fourths of patients with Alzheimer’s disease or frontal-lobe degeneration had MRI-detected biomarker levels that correlated with the diagnoses, suggesting MRI has potential as a screening tool for the conditions, investigators reported.

MRI-predicted values for total tau and β-amyloid ratio (tt/Aβ) in gray matter correctly pinpointed the diagnosis in 75% of patients with genetically or… MRI May Tell Alzheimer’s from Other Dementias   



Study finds that sleep apnea and Alzheimer’s are linked

A new study looking at sleep-disordered breathing (SDB) and markers for Alzheimer’s disease (AD) risk in cerebrospinal fluid (CSF) and neuroimaging adds to the growing body of research linking the two.

But this latest study also poses an interesting question: Could AD in its “preclinical stages” also lead to SDB and explain the increased… Study finds that sleep apnea and Alzheimer’s are linked   



Impaired recovery from inflammation linked to Alzheimer’s disease

New research from Karolinska Institutet shows that the final stage of the normal inflammatory process may be disrupted in patients with Alzheimer’s disease. A study published in the journal Alzheimer’s & Dementia shows that levels in the brain and cerebrospinal fluid of the molecules necessary for tissue recovery through the clearance of harmful inflammatory… Impaired recovery from inflammation linked to Alzheimer’s disease   



Going Home (A short film on Dementia)

dementia patients8 - motor development1 - amnestic mild cognitive impairment1 - arteriosclerotic dementia1 - melancholia2 - brain health1 - dementing illness1 - mental confusion4 - good sleep habits1 - angina1 - dementia decline1 - arterial plaques1 - decline of memory1 - cognitive reserve1 - hallucinations1 - significant memory loss1 - beta-secretase-1 protein1 - dantrolene1 - cognition2 - failing memory1 - igfbp-31 - plaque in alzheimer's disease1 - senility1 - psychiatrist's bible1 - risk of dementia12 - petersen1 - miller fisher1 - novel proteins1 - enlarged ventricles1 - anticholinergics1 -