Site updated at Wednesday, 22 June 2016

Living with Dementia


Structural Imaging

An important advance in the evaluation of people with suspected dementia of the Alzheimer type is the use of structural imaging to assess in vivo neuroanatomical changes. This technique can also be used in conjunction with neuropsychological test data to better understand the relationship between the structural brain changes and the cognitive… Structural Imaging   

Memory test ‘identifies Alzheimer’s early’

Doctors will be able to identify the initial signs of Alzheimer’s disease earlier thanks to a new 10 minute, picture-based memory test.

The iPad-based test will enable GPs to test patients in high street surgeries, rather than having to refer them to specialist clinics, which could drive up diagnosis rates.

Currently only 40 per… Memory test ‘identifies Alzheimer’s early’   

A micro-RNA as a key regulator of learning and Alzheimer’s disease

Proteins are the molecular machines of the cell. They transport materials, cleave products or transmit signals - and for a long time, they have been a main focus of attention in molecular biology research. In the last two decades, however, another class of critically important molecules has emerged: small RNA molecules, including micro-RNAs. It… A micro-RNA as a key regulator of learning and Alzheimer’s disease   

Atypical form of Alzheimer’s disease may be present in a more widespread number of patients

Neuroscientists at Mayo Clinic in Florida have defined a subtype of Alzheimer’s disease (AD) that they say is neither well recognized nor treated appropriately.

The variant, called hippocampal sparing AD, made up 11 percent of the 1,821 AD-confirmed brains examined by Mayo Clinic researchers - suggesting this subtype is relatively widespread in the general… Atypical form of Alzheimer’s disease may be present in a more widespread number of patients   

Cajal-Retzius cell loss and amyloidosis in Alzheimer’s disease

Cajal-Retzius cells are reelin-secreting neurons in the marginal zone of the neocortex and hippocampus. However, the relationship between Cajal-Retzius cells and Alzheimer’s disease is unknown. Dr. Jinbo Deng and team from Henan University in China revealed that the number of Cajal-Retzius cells markedly reduced with age in both wild type and in mice over-expressing… Cajal-Retzius cell loss and amyloidosis in Alzheimer’s disease   

Building block for memory and learning identified

Researchers have been fascinated for a long time by learning and memory formation, and many questions are still open. Bochum-based neuroscientists Prof Dr Denise Manahan-Vaughan and Dr Hardy Hagena have discovered a key building block for this complex process. A particular neurotransmitter receptor, namely the metabotropic glutamate receptor 5, is a switch for activating… Building block for memory and learning identified   

Living with Dementia: I’m Still Here

kahlbaum3 - movement disorder2 - terminal cognitive failure1 - progressive dementia3 - beta amyloid plaques1 - health and wellness1 - emission computed tomography1 - tau3 - enlarged ventricles1 - temporal orientation1 - body mass index2 - loss of judgement1 - mediterranean1 - myelination1 - skin problems1 - obesity2 - dementia causes3 - dopamine-producing nerve cells1 - development of parkinson's1 - amyloid protein1 - psychiatric status rating scales1 - acute excitement1 - myxoedema1 - autosomal dominant gene mutation1 - brain cell damage2 - behavioral signs1 - nilotinib1 - inherited condition1 - aortic valve stenosis2 - ad prognosis1 -