Dementia Today.net

Site updated at Wednesday, 22 June 2016

Living with Dementia

Huntingtons Disease

Possible New Treatment for Huntington’s Disease

Treatment that increases brain levels of a crucial regulatory enzyme may slow the loss of brain cells that characterize Huntington’s disease (HD) and other neurodegenerative disorders, according to this study. Increased expression of Sirt1, one of a family of enzymes called sirtuins, in the brain of a mouse model of HD protected against neurodegeneration.… Possible New Treatment for Huntington’s Disease   



Human model of Huntington’s disease created from skin’s stem cells

An international consortium of Huntington’s disease experts, including several from the Sue & Bill Gross Stem Cell Research Center at UC Irvine, has generated a human model of the deadly inherited disorder directly from the skin cells of affected patients.

The re-created neurons, which live in a petri dish, will help researchers better understand… Human model of Huntington’s disease created from skin’s stem cells   



Berkeley Lab Scientists Help Develop Promising Therapy for Huntington’s Disease

There’s new hope in the fight against Huntington’s disease. A group of researchers that includes scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice.

The compound is a synthetic antioxidant that targets mitochondria, an organelle within cells… Berkeley Lab Scientists Help Develop Promising Therapy for Huntington’s Disease   



‘Disease in a dish’ approach could aid Huntington’s disease discovery efforts

Creating induced pluripotent stem cells or iPS cells allows researchers to establish “disease in a dish” models of conditions ranging from Alzheimer’s disease to diabetes. Scientists at Yerkes National Primate Research Center, Emory University have now applied the technology to a model of Huntington’s disease (HD) in transgenic nonhuman primates, allowing them to conveniently… ‘Disease in a dish’ approach could aid Huntington’s disease discovery efforts   



Alzheimer’s Disease

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