Site updated at Wednesday, 22 June 2016

Living with Dementia

Lewy Bodies

New clue to Parkinson’s

A new study finds that a protein key to Parkinson’s disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging existing disease paradigms and suggesting a new therapeutic approach.

“Our data show that alpha-synuclein was essentially mistakenly characterized as a natively unfolded… New clue to Parkinson’s   

New study supports view that Lewy bodies are not the primary cause of cell death in PD

The pathology of Parkinson’s disease is characterized by a loss of dopamine-producing neurons in the pars compacta of the substantia nigra (SN), an area of the brain associated with motor control, along with the development of α-synuclein (αS) protein in the form of Lewy bodies (LB) in the neurons that survive. The spread of… New study supports view that Lewy bodies are not the primary cause of cell death in PD   

Living with Dementia

degree of dementia1 - memory disorder1 - cholesterol1 - aging5 - risk for cognitive decline1 - alpha-synuclein7 - miller fisher1 - neuronal membrane1 - developing alzheimers2 - sundowning2 - alzheimer's brain1 - improved recognition1 - basal ganglia1 - tremor2 - cognitive deficits1 - journal of clinical nursing1 - mini-mental state examination2 - spect1 - α-synuclein2 - adam10 enzyme1 - stress2 - problems with speech1 - poor judgment2 - carotid ultrasound1 - medicare1 - single-photon emission computed tomography1 - alzheimer's warning signs1 - brain insulin1 - increased dementia risk1 - korsakoff amnesic syndrome1 -