Site updated at Wednesday, 22 June 2016

Living with Dementia

Lewy Bodies

New clue to Parkinson’s

A new study finds that a protein key to Parkinson’s disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging existing disease paradigms and suggesting a new therapeutic approach.

“Our data show that alpha-synuclein was essentially mistakenly characterized as a natively unfolded… New clue to Parkinson’s   

New study supports view that Lewy bodies are not the primary cause of cell death in PD

The pathology of Parkinson’s disease is characterized by a loss of dopamine-producing neurons in the pars compacta of the substantia nigra (SN), an area of the brain associated with motor control, along with the development of α-synuclein (αS) protein in the form of Lewy bodies (LB) in the neurons that survive. The spread of… New study supports view that Lewy bodies are not the primary cause of cell death in PD   

Living with Dementia: I’m Still Here

olive oil1 - cerebrovascular disease1 - neurotoxic oligomers1 - mitochondrial function1 - dementia care program1 - alzheimer's researchers1 - astro-gliosis1 - coping strategies1 - undertreatment of dementia1 - hip fracture1 - blood markers1 - healthy weight1 - dantrolene1 - single-photon emission computed tomography1 - inheritable dominant disease1 - missing person1 - neurofibrillary tangles3 - mini-cognitive assessment1 - causes of the dementia1 - amyloid plaques13 - cholesterol-lowering drugs1 - quantitative structural neuroimaging1 - confabulation1 - dementia friends1 - dementias first signs1 - memory disorder1 - decline in cognitive functioning1 - pomegranate1 - melancholia2 - semantic dementia1 -