Dementia Today.net

Site updated at Wednesday, 22 June 2016

Living with Dementia

Mild Cognitive Impairment

Clinical Conclusions

Using an evidence-based review of the literature, the Quality Standards Subcommittee of the American Academy of Neurology made three levels of recommendation for clinical practice related to the diagnosis and evaluation of individuals with mild cognitive impairment and dementia (Knopman et al. 2001; Petersen et al. 2001): standards were based on patient management… Clinical Conclusions   



Sleep apnea linked to memory decline, dementia

Older women who have sleep apnea may be more likely to develop memory problems and dementia, according to a new study.

It’s not clear yet whether treating the sleep apnea can help prevent that memory decline -  but researchers say future studies should address that question.

“It makes sense that good sleep is going… Sleep apnea linked to memory decline, dementia   



Differential diagnosis of dementia

Aging and cognitive decline

There is a natural age-associated modification in cognition. As a consequence, it can be problematic distinguishing between cognitive impairment associated with normal aging and early dementia. In addition, ‘mild cognitive impairment’ (MCI) can be experienced. This is characterized by an abnormal level of cognitive impairment, albeit that it does not… Differential diagnosis of dementia   



Memory test ‘identifies Alzheimer’s early’

Doctors will be able to identify the initial signs of Alzheimer’s disease earlier thanks to a new 10 minute, picture-based memory test.

The iPad-based test will enable GPs to test patients in high street surgeries, rather than having to refer them to specialist clinics, which could drive up diagnosis rates.

Currently only 40 per… Memory test ‘identifies Alzheimer’s early’   



Test Combination Helps Predict Alzheimer’s Disease Risk

With age, forgetfulness and other signs of memory loss sometimes appear, prompting elderly individuals to seek a medical evaluation amid fears that they may be experiencing early symptoms of Alzheimer’s disease (AD), the most common type of dementia among Americans aged 65 and older.

But even when early memory problems suggest the potential for… Test Combination Helps Predict Alzheimer’s Disease Risk   



Hypertension affects brain capacity

Can dementias and mild cognitive impairment be influenced in their course by diseases and risk factors? This is the subject of a study reported by Thorleif Etgen and co-authors in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2011; 108[44]: 743-50).

Increasingly larger numbers of people are affected by mild cognitive impairments… Hypertension affects brain capacity   



People with Early Alzheimer’s Disease May Be More Likely to Have Lower BMI

Studies have shown that people who are overweight in middle age are more likely to develop Alzheimer’s disease decades later than people at normal weight, yet researchers have also found that people in the earliest stages of Alzheimer’s disease are more likely to have a lower body mass index (BMI). A current study examines… People with Early Alzheimer’s Disease May Be More Likely to Have Lower BMI   



Eating fish reduces risk of Alzheimer’s disease

People who eat baked or broiled fish on a weekly basis may be improving their brain health and reducing their risk of developing mild cognitive impairment (MCI) and Alzheimer’s disease, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

“This is the first study to… Eating fish reduces risk of Alzheimer’s disease   



Blurry line in diagnosing early Alzheimer’s: study

The revised definition of a brain condition called mild cognitive impairment means that many people now considered to have mild or early Alzheimer’s disease could easily be given that diagnosis instead, suggests a new study.

Mild cognitive impairment is already seen by doctors as the first hint of a future Alzheimer’s diagnosis in many… Blurry line in diagnosing early Alzheimer’s: study   



Overeating can double the risk of memory loss

A new US study has found that people who eat too much in their seventies or older are doubling their risk of memory impairment, or mild cognitive impairment (MCI), which can be an early sign of Alzheimer’s disease.

The study Daily Caloric Intake, Aging and Mild Cognitive Impairment by Yonas E Geda, associate professor… Overeating can double the risk of memory loss   



Scientists reveal early diagnostic clues for AD using advanced brain imaging technology

Alzheimer’s disease (AD) is a major neurodegenerative disorder that affects millions of people worldwide. New and accurate techniques for early diagnosis are critical. Pravat K. Mandal, PhD, and his colleagues have developed a completely non-invasive brain imaging technique to measure specific brain chemical changes. This provides a signature of the early stages of AD… Scientists reveal early diagnostic clues for AD using advanced brain imaging technology   



Alzheimer’s disease in men linked to low levels of hormone, IGF-1

Low serum levels of insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) are associated with Alzheimer’s Disease in men, but not women, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

IGF-1 and IGFBP-3 are involved in longevity and could be… Alzheimer’s disease in men linked to low levels of hormone, IGF-1   



Combination of imaging exams improves Alzheimer’s diagnosis

A combination of diagnostic tests, including imaging and cerebrospinal fluid biomarkers can improve prediction of conversion from mild cognitive impairment (MCI) to Alzheimer’s disease, according to a new study published online in the journal Radiology.

“Because new treatments are likely to be most effective at the earliest stages of Alzheimer’s disease, there is great… Combination of imaging exams improves Alzheimer’s diagnosis   



Tracing the impact of amyloid beta in mild cognitive impairment

The amount of amyloid β (Aβ) in the brains of people with mild cognitive impairment (MCI) is contributing to early memory loss, and increases with severity of symptoms, finds a study in BioMed Central’s open access journal Alzheimer’s Research & Therapy. The non-invasive study which used 18F-florbetaben to find Aβ plaques in brain scans… Tracing the impact of amyloid beta in mild cognitive impairment   



Improved Detection of Frontotemporal Degeneration May Aid Clinical Trial Efforts

A series of studies demonstrate improved detection of the second most common form of dementia, providing diagnostic specificity that clears the way for refined clinical trials testing targeted treatments. The new research is being presented by experts from the Perelman School of Medicine at the University of Pennsylvania at the American Academy of Neurology’s… Improved Detection of Frontotemporal Degeneration May Aid Clinical Trial Efforts   



Memory problems ‘earliest sign’ of Alzheimers

Elderly people who suspect they may be losing their memory but score normal results when tested by doctors may still be at higher risk of Alzheimer’s, experts have warned.

Five studies presented at the Alzheimer’s Association conference in Boston on Wednesday found that people who were clinically healthy but anxious about memory lapses… Memory problems ‘earliest sign’ of Alzheimers   



Johns Hopkins research may improve early detection of dementia

Using scores obtained from cognitive tests, Johns Hopkins researchers think they have developed a model that could help determine whether memory loss in older adults is benign or a stop on the way to Alzheimer’s disease.

The risk of developing dementia increases markedly when a person is diagnosed with mild cognitive impairment, a noticeable… Johns Hopkins research may improve early detection of dementia   



Stress reduction through meditation may aid in slowing the progression of Alzheimer’s disease

It’s well known that the brains of meditators change, but it’s not entirely clear what those changes mean or how the changes might benefit the meditator. A new pilot study led by researchers at Beth Israel Deaconess Medical Center suggests that the brain changes associated with meditation and stress reduction may play an important… Stress reduction through meditation may aid in slowing the progression of Alzheimer’s disease   



Blood test identifies those at-risk for cognitive decline, Alzheimer’s within 3 years

Researchers have discovered and validated a blood test that can predict with greater than 90 percent accuracy if a healthy person will develop mild cognitive impairment or Alzheimer’s disease within three years.

Described in Nature Medicine published online today, the study heralds the potential for developing treatment strategies for Alzheimer’s at an earlier stage,… Blood test identifies those at-risk for cognitive decline, Alzheimer’s within 3 years   



Dementia risk quadrupled in people with mild cognitive impairment

In a long-term, large-scale population-based study of individuals aged 55 years or older in the general population researchers found that those diagnosed with mild cognitive impairment (MCI) had a four-fold increased risk of developing dementia or Alzheimer’s disease (AD) compared to cognitively healthy individuals. Several risk factors including older age, positive APOE-ɛ4 status, low… Dementia risk quadrupled in people with mild cognitive impairment   



I have Alzheimer Disease

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