Site updated at Wednesday, 22 June 2016

Living with Dementia

Neurofibrillary Tangles

Inflammatory mediator enhances plaque formation in Alzheimer’s disease

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder that causes progressive cognitive impairment and memory loss. Now, a new study published by Cell Press in the September 8 issue of the journal Neuron identifies a previously unrecognized link between neuroinflammation and the classical pathological brain changes that are the hallmark of the disease. In… Inflammatory mediator enhances plaque formation in Alzheimer’s disease   

Untangling the mysteries of Alzheimer’s

One of the most distinctive signs of the development of Alzheimer’s disease is a change in the behavior of a protein that neuroscientists call tau. In normal brains, tau is present in individual units essential to neuron health. In the cells of Alzheimer’s brains, by contrast, tau proteins aggregate into twisted structures known as… Untangling the mysteries of Alzheimer’s   

Team Unravels Central Mystery of Alzheimer’s

Scientists at The Scripps Research Institute (TSRI) have shed light on one of the major toxic mechanisms of Alzheimer’s disease. The discoveries could lead to a much better understanding of the Alzheimer’s process and how to prevent it.

The findings, reported in the April 10, 2013 issue of the journal Neuron, show that brain… Team Unravels Central Mystery of Alzheimer’s   

Alzheimer’s Disease

progression of dementia1 - beta-secretase-1 protein1 - mitochondria1 - stage dementia1 - motoric cognitive risk syndrome1 - dantrolene1 - tfp5 treatment1 - prichard1 - symptoms of alzheimer's2 - alzheimer's plaques1 - lewy body parkinson's disease1 - amylin deposition1 - confabulation1 - cause of alzheimer's1 - electroencephalogram1 - psychiatric status rating scales1 - smile study1 - neuropsychological tests1 - incident dementia1 - nilotinib1 - progressive dementia3 - major depression1 - insomnia2 - references1 - cholinesterase inhibitors1 - app3 - neurodegenerative disorder4 - frontotemporal dementia8 - anterograde amnesia10 - changes in mood1 -