Substantia Nigra
Parkinson’s Disease is a common disorder of deep brain structures that help control movement. Over time, many people with Parkinson’s disease develop Parkinson’s Disease Dementia. The majority of Parkinson’s Disease patients over the age if 65 develop dementia within a few years. Even younger people with Parkinson’s Disease can develop dementia one community…
New modeling of brain’s circuitry may bring better understanding of Parkinson’s disease
Researchers from the School of Science at Indiana University-Purdue University Indianapolis have developed a mathematical model of the brain’s neural circuitry that may provide a better understanding of how and why information is not transmitted correctly in the brains of Parkinson’s disease patients. This knowledge may eventually help scientists and clinicians correct these misfires.…
New study supports view that Lewy bodies are not the primary cause of cell death in PD
The pathology of Parkinson’s disease is characterized by a loss of dopamine-producing neurons in the pars compacta of the substantia nigra (SN), an area of the brain associated with motor control, along with the development of α-synuclein (αS) protein in the form of Lewy bodies (LB) in the neurons that survive. The spread of…